Biologics Is Fastest Growing Segment Fueling The Growth Of Calcineurin Inhibitor Market
Calcineurin Inhibitor Market |
The global Calcineurin Inhibitor Market is estimated to be valued at US$ 10.07 Bn in 2023 and is expected to exhibit a CAGR of 10% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.
Market Overview:
Calcineurin inhibitors are immunosuppressants that help prevent organ
transplant rejection by suppressing T-cell activation. They act by inhibiting
the action of calcineurin, an enzyme involved in signaling pathways of T-cell
activation. Calcineurin inhibitors find application in transplantation
procedures such as kidney, heart and liver transplantation.
Market Key Trends:
One of the key trends in the calcineurin inhibitor market is the increasing
preference towards biologics. Biologics act as potent and specific alternatives
to first generation immunosuppressants with lesser side effects. For instance,
belatacept, a selective T-cell costimulation blocker, demonstrated superior
long-term kidney function compared to calcineurin inhibitors in renal
transplant recipients. Rising awareness about advantages of biologics and their
approval for wider clinical indications is expected to drive their demand,
replacing conventional calcineurin inhibitors to a certain extent in the coming
years.
Segment Analysis
The calcineurin inhibitor market is dominated by the cyclosporine segment.
Cyclosporine is one of the oldest and most commonly prescribed calcineurin
inhibitors. It is mostly used for the prevention of organ transplant rejection
during kidney, heart, and liver transplantations. The segment held around 60%
of the global market share in 2023 owing to the wide acceptance and
availability of generic forms of cyclosporine.
Key Takeaways
The
Global Calcineurin Inhibitor Market Demand is expected to witness high
growth, exhibiting a CAGR of 10%
over the forecast period, due to an increasing number of organ transplantation
surgeries globally.
Regional analysis
North America dominated the global calcineurin inhibitor market and accounted
for over 30% of the global market share in 2023. This is attributed to factors
such as the presence of developed healthcare infrastructure, high adoption of
innovative transplantation drugs, and favorable government programs. Asia
Pacific is anticipated to be the fastest-growing region during the forecast
period owing to rising awareness about transplantation and increasing
healthcare spending in major APAC countries.
Key players
Key players operating in the calcineurin inhibitor market are Novartis AG,
Astellas Pharma Inc., LEO Pharma A/S, Allergan, Inc., Pfizer Inc., Sanofi SA,
GlaxoSmithKline plc, Johnson & Johnson Services, Inc., Merck & Co.,
Inc., Roche Holding AG, Bristol Myers Squibb Company, AbbVie Inc., Eli Lilly
and Company, Takeda Pharmaceutical Company Limited, Mylan N.V. Novartis, with
its generic version of cyclosporine, dominates the market.
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