Biologics Is Fastest Growing Segment Fueling The Growth Of Calcineurin Inhibitor Market

 Calcineurin Inhibitor Market


The global Calcineurin Inhibitor Market is estimated to be valued at US$ 10.07 Bn in 2023 and is expected to exhibit a CAGR of 10% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights.

Market Overview:
Calcineurin inhibitors are immunosuppressants that help prevent organ transplant rejection by suppressing T-cell activation. They act by inhibiting the action of calcineurin, an enzyme involved in signaling pathways of T-cell activation. Calcineurin inhibitors find application in transplantation procedures such as kidney, heart and liver transplantation.

Market Key Trends:
One of the key trends in the calcineurin inhibitor market is the increasing preference towards biologics. Biologics act as potent and specific alternatives to first generation immunosuppressants with lesser side effects. For instance, belatacept, a selective T-cell costimulation blocker, demonstrated superior long-term kidney function compared to calcineurin inhibitors in renal transplant recipients. Rising awareness about advantages of biologics and their approval for wider clinical indications is expected to drive their demand, replacing conventional calcineurin inhibitors to a certain extent in the coming years.


Segment Analysis
The calcineurin inhibitor market is dominated by the cyclosporine segment. Cyclosporine is one of the oldest and most commonly prescribed calcineurin inhibitors. It is mostly used for the prevention of organ transplant rejection during kidney, heart, and liver transplantations. The segment held around 60% of the global market share in 2023 owing to the wide acceptance and availability of generic forms of cyclosporine.

Key Takeaways
The Global Calcineurin Inhibitor Market Demand is expected to witness high growth, exhibiting a CAGR of 10% over the forecast period, due to an increasing number of organ transplantation surgeries globally.

Regional analysis
North America dominated the global calcineurin inhibitor market and accounted for over 30% of the global market share in 2023. This is attributed to factors such as the presence of developed healthcare infrastructure, high adoption of innovative transplantation drugs, and favorable government programs. Asia Pacific is anticipated to be the fastest-growing region during the forecast period owing to rising awareness about transplantation and increasing healthcare spending in major APAC countries.

Key players
Key players operating in the calcineurin inhibitor market are Novartis AG, Astellas Pharma Inc., LEO Pharma A/S, Allergan, Inc., Pfizer Inc., Sanofi SA, GlaxoSmithKline plc, Johnson & Johnson Services, Inc., Merck & Co., Inc., Roche Holding AG, Bristol Myers Squibb Company, AbbVie Inc., Eli Lilly and Company, Takeda Pharmaceutical Company Limited, Mylan N.V. Novartis, with its generic version of cyclosporine, dominates the market.

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