Oligonucleotides
are short sequences of nucleic acid polymers used as probes and primers in DNA
sequencing, DNA microarrays, polymerase chain reaction (PCR), oligonucleotide
synthesis and hybridization assays. The oligonucleotide synthesis market is
driven by the increasing demand for custom oligonucleotides for research and
molecular diagnostics. Custom oligonucleotides facilitate disease diagnostics,
personalized medicine and genomic analysis.
The
global oligonucleotide synthesis market is estimated to be valued at US$ 3,962.67 Mn in 2023 and is expected
to exhibit a CAGR of 11% over the
forecast period 2023 to 2030, as
highlighted in a new report published by Coherent Market Insights.
Market key trends:
The emergence of new applications of oligonucleotides such as therapeutics,
antisense oligonucleotides, small interfering RNA (siRNA) and micro RNA (miRNA)
have propelled market growth. Antisense oligonucleotides inhibit protein
expression by binding to complementary messenger RNA sequences and inhibiting
translation. siRNA are used to turn off specific genes for research and
potentially therapeutic purposes. Both offer promising alternatives to small
molecule drugs and biologics with improved targeting and fewer side effects.
Advancements in oligonucleotide synthesis technologies such as phosphoramidite
chemistry have enabled mass production of oligonucleotides at reduced cost,
further supporting market expansion.
Segment
Analysis
The global oligonucleotide synthesis market is dominated by DNA
oligonucleotides. DNA oligonucleotides find widespread application in PCR,
sequencing, gene synthesis and molecular diagnostics. DNA oligonucleotides are
short single stranded DNA polymers that are synthesized in the laboratory and
have applications in various life science disciplines including biotechnology
research, molecular and cellular biology, genomic and proteomic analysis.
Key Takeaways
The
Global
Oligonucleotide Synthesis Market Size
is expected to witness high growth over the forecast period of 2023
to 2030. The global oligonucleotide synthesis market is estimated to be valued
at US$ 3962.67 Mn in 2023 and is expected to exhibit a CAGR of 11% over the
forecast period 2023 to 2030.
North
America currently dominates the oligonucleotide synthesis market. Increased
funding for research activities from government organizations along with
presence of leading oligonucleotide synthesis companies in the region has made
North America the largest market. The Asia Pacific region is expected to
witness the fastest growth owing to increasing investments by key players,
rising awareness about personalized medicine and growing life science research
activities in countries such as China and India.
Key players operating in the oligonucleotide synthesis market are Thermo Fisher
Scientific, Sigma-Aldrich Corporation, GE Healthcare, Integrated DNA
Technologies, Inc., TriLink Biotechnologies€TM, Inc, BioAutomation Corporation,
Twist Bioscience, Shanghai SynTheAll Pharmaceutical Co., CUSABIO Technology
LLC, Synbio Technologies, GENEWIZ, Eurofins Scientific, Agilent Technologies,
Kaneka Eurogentec S.A., and LGC, Biosearch Technologies. These companies
continuously focus on new product launches and expansion of their existing
product portfolios to strengthen their positions in the global market.
Get
more insights on this topic:
https://www.marketwebjournal.com/oligonucleotide-synthesis-market-trends-size-and-share-analysis/
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